I didn't go there with kids so I don't know any kid-friendly places
are you asking for restaurant or hotel recommendations?
I do know there are some cool restaurants in the gaslamp district area. we only went to the top of the marriott though to check out the view of Petco Park
so I can't make any restaurant recommendation there. when we were there, they even had a jazz festival going on at the time. and of course there's always Old Town which also has lots of great restaurants. if you like mexican food, I heard the Mexican Cafe is really good.
if you're looking for places to stay, then it would be more fun to stay somewhere in the gaslamp district.
in La Jolla, you'll have to check out the Cove of course. I think you may even be able to see lots of seals there right now. and like I said, the restaurants I've been to are geared mostly for adults
I've never been to the Wild Animal Park